72 Comments
May 17Liked by BowTied Biohacker

Thanks, yes ! - something like that -on the days after a long flight, some major jet lag and sleep deprivation where the usual 4 cups of espresso does not make a dent

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Yeah that'll help a little bit. Rhodiola Rosea is another solid choice to stack with. https://nootropicsdepot.com/rhodiola-rosea-capsules-salidroside/?afmc=BIOHACKER10

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May 15Liked by BowTied Biohacker

One more question, might be dumb but how do you take your supplements? I have magnesium, zinc, creatine and protein powder for the gym. Looking to add tongkat ali to boost test, but you have mentioned adding bromantane and l-tyrosine. Appreciate your anticipated response

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How do I take them? As needed and with doctor approval.

I'm not sure what your question is.

Bromantane and L-Tyrosine aren't test boosters. Tongkat Ali may marginally boost test, but it's only the finishing touch to a high T diet and lifestyle. If you're going to take tongkat ali, nootropics depot is the only company I'd trust.

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May 15Liked by BowTied Biohacker

Why do I sleep so much better on days I take ashwagandha? I don’t like it though because it makes me feel a little too lethargic but is there anything alternative I can take that would help sleep to the same extent? Thanks!

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Seems like your baseline is high stress. Aswagandha will make you lethargic for sure.

You should read my article on sleep supplements:

https://bowtiedbiohacker.com/p/a-biohackers-guide-to-sleep-supplements

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May 14Liked by BowTied Biohacker

Hey BTB,

Maybe more comprehensive question but I prefer to have answer on this topic from someone I trust not from random Reddit guy.

I know nothing from your answer will be medical advice, I just would like to know what you would on my spot.

I plan to run low 150mg/weekly dose of testosterone (1st using injectable substance) 28yo, 675 T, currently 10%bf I plan to start once I hit real 9% because of aromatase.

- most important what brand/ what should I look for the product to have before I buy (if needed)

- at this dose would you still recommend 2/week

- at this dose is AI enough in table form like DIM/I3C or you would do (in my place) injectable?

- is it still safe to run just Testo at this dose in terms of fertility/ post cure production of T or should one combine with hcg or something?

- how long would you run such a first cycle and what beside T, E2, prolactin you would test.

I plan run test every 2 weeks.

Thanks a lot. And still I would love to see some article from you about something like how to safely start with PED, although I get it if it might be slippery slope thing to do for masses.

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I mean 150mg a week could cause high estradiol in a lot of dudes because it's more than the body makes naturally. But you also don't wanna use an AI for HRT+.

So.... twice a week? probably not. every other day would be better. 150/3.5 = ~43mg every other day

Estradiol won't be as high, hormones will be a lot more stable. if it's still a tad too high, that's when 100mg DIM and 500mg CDG twice per day can help you. Shouldn't need MORE than that for e2 management.

As far as brand goes, pharma test cyp or enanth is fine.

If you're planning on doing a cycle, I think 200mg is the minimum you should shut yourself down for, if not 250mg. At least get some gains out of it.

I personally wouldn't cycle, staying on HRT+ is much better. Coming off SUCKS regardless of how you do it. But if you must, enclomiphene monotherapy after 4-6 months of test should get the job done. Would hCG make it easier? Yes, but hCG is incredibly complicated to dial in for a noobie and would almost certainly necessitate and AI, so I wouldn't personally bother but up to you.

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May 14Liked by BowTied Biohacker

Idk if this is a biohacking Q or not but I cannot find a straight answer: what is the biological mechanism that will increase my endurance running speed, ie I run at a given pace for 30 min in zone 4 and I am wondering what in my body will adapt to that pace and require less strain to achieve the same pace and whether it is predictable and manipulatable by exogenous supplements

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There are so many!

Oxygen carrying capacity

Enhanced ATP production

Mitochondrial biogenesis

PPAR delta upregulation

Enhanced lipolysis/glucose retention

Enhanced nutrient uptake

Increased slow twitch muscle fiber

Angiogenesis

Lactate threshold improvement

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A lot of potential things to focus on and progress. Gracias fren

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May 13Liked by BowTied Biohacker

When do you think someone should consider hopping on TRT? Is it a numbers things like if you are under 550 should probably be omit or is it based more on how you feel ?

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100% based on how you feel and also should be LEAN 12% bf max (means you have very cut 6 pack abs), eating right, lifting 4x a week or more, sleeping right, getting sun, competing and doing high T activities. Your body won't produce a lot of T unless you give it reasons to

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Hi,

I’m training Muay Thai and gym daily 5x per week. Do you have any suggestions for recovery?

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Make sure you're at maintenance at least, if not a caloric surplus! Make sure protein is 1g per lb of bodyweight, MINIMUM. Make sure you're getting 8 hours of sleep, preferably going to bed before midnight. If you feel weak or otherwise "burnt out" take a day off, do a "deload week" in the gym. Get bloodwork and check IGF-1 Levels. You want those to be 250+ ideally. You wanna make sure testosterone and estradiol are in the upper end of the reference range as well.

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Thanks!

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I have to look at your lucid dreaming post still, t in the mean time any thoughts on lack of dreaming being a nutrient deficiency? Just got off a successful gut cleanse and looking to fix what causes lack of dreams. Oura ring says my sleep scores are great so I’m thinking nutrition of some kind

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You're possible on to something here. Have you downloaded cronometer and tracked your food intake for a few weeks to spot deficiencies?

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I use MyfitnessPal, which does some of that tracking. Do you recommend cronometer over MFP?

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I'll check this out. Thank you

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I think I my sweat smells like ammonia. At least, it's quite unpleasant.

It makes sense since I'm cutting and have less fuel (was on low carb before, so cut lots of fat from daily). I try to eat more carbs but seems like it's not enough, I also drink more than before. I keep your recommendation at 1.25 grams per lbs and 60g of fat per day, and rest is carbs but with 800-700ish c. deficit a day that's not much left over.

Maybe would need to reduce fat a little more?

Anything I can do to avoid that smell? I don't think it's optimal health wise either, seems like my body tries to burn protein? Shall I just reduce the daily deficit even if it means I'll get to my desired 10% much later? Ty

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author

Few things going on here

Maybe your protein consumption is higher than you think it is

Maybe you're burning more calories than you think you are and your body is using excess protein for energy.

Perhaps your fat is higher and your carbs are lower than you think?

There is 100% a measuring error going on here :)

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May 18Liked by BowTied Biohacker

Ty. I track everything I eat to the grams with cronometer. The only dubious part there is things like egg or banana where I just put medium instead of measuring.

I even adjusted my protein need to my already lower weight.

So it's probably the burning part. I use apple watch but not wearing it for little walks usually also maybe I underestimate my box trainings.

So when would my body use protein for energy? Above a certain deficit? Or it's more like I need to cover x amount of calories from carbs to avoid that.

I only thought about calorie deficit, and I think it's under 1000 per day as I don't see more than 2 pounds per week weight loss.

So maybe I need certain amount of carbs per let's say 500 calories burned via exercise? No matter the deficit?

Thanks.still trying to understand this topic. And the closer to 10% I get the more important this will be.

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"So when would my body use protein for energy? Above a certain deficit? Or it's more like I need to cover x amount of calories from carbs to avoid that."

It's a little bit of both.

Dial back the deficit a little and be patient, but also up the carbs. I can't tell you exactly how much because that's going to be individual to you and will require some trial and error on your part.

You got this dude!!!

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May 17Liked by BowTied Biohacker

I didn't have this issue before... I think I have this since switching from keto and started cutting, increasing protein, reducing fat, more cardio.

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Can someone link me to the BPC-157 dosage thread please? Thank you

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I've been doing AM cardio consistently now since you first recently mentioned it on an X post and most days I feel great from it.

But a few times I have tried taking some noots just to see if I can take it to another level but every time I feel worse, brain fog, not as sharp etc.

Presuming the dosages are correct what could be going on here?

You recently said that Semax, bromantane and sabroxy are your 3 favorite ways to test dopaminergic function... And if you don't feel powerful, focused and uplifted on them, it means it's time for a dopamine fast. Could this be what's needed? It's not that I just dont feel the benefits from them, they have the opposite effect.

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Sabroxy is sedating if you take too much. 100mg to 300mg is the sweet spot for many,

Bromantane is the same if you dose too high, remember it's also an anxiolytic and adaptogen. It'll make u feel too chill, body might feel heavy etc

Semax is totally a "less is more" compound. 300mcg is more than enough for many. you might also be a rare nonresponder to semax too.

Dopamine fast is probably a good idea though. Everyone needs 1 or 2 a yr IMO

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What would you recommend on days on long days of hectic travel/ sightseeing. Tested out alpha-gpc but feels like its not right for a whole long day

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Hmm perhaps Dynamax?

https://nootropicsdepot.com/dynamax-plus/?afmc=BIOHACKER10 (Can use BIOHACKER10 for 10% off)

What's the issue, you just need more energy? That would help a lot

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Got blood work done recently and saw my LH levels were much higher than normal with lower T levels. I know TRT is an option but are there any supplements that can naturally lower my LH to get it back in range?

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If you lower your LH your testosterone will go even lower. You have a problem with your testicles. They aren't responding well to LH so your pituitary is compensating by releasing more. You need to get that checked out by a doctor, but TRT might end up being the only case. This is a rare cause of low T and unlike most people on TRT, sounds like you might ACTUALLY need it :)

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I really like the taste of this greek yogurt made by Chobani and the macros are great. When I add frozen berries, cinnamon, cacao powder it really helps control a sweet tooth. It's a staple in my diet.

Wanted to ask at a glance do any of the ingredients raise immediate red flags to you?

https://www.chobani.com/products/yogurt/zero-sugar/vanilla-large-size-tub

Ingredients:

"Ultra-filtered nonfat milk**, water, skim milk†, allulose†, contains 2% or less of: natural flavors, tapioca flour, citrus fiber, guar gum, sea salt, stevia leaf extract (reb m), monk fruit extract, vanilla extract, cultures. **Ingredient not found in regular yogurt. †Includes a dietarily insignificant amount of sugar."

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Looks pretty good to me

100% natty which is a plus

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What is your go-to focus stack?

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Hey brother. Hope you're well.

Trying hard to improve my REM sleep. It sits at around 10-14%. Trying to get it up to around 18-20%.

I take melatonin and magnesium before bed.

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author

More darkness in your bedroom

Keep the temperature in the 60s

Make sure you get your morning sunlight at least 10-15 mins

Reduce caffeine intake and cut it off before noon. Try to sleep before midnight.

Supplement with CDP choline and gingko. Can consider huperzine a.

Eliminate any other stress you may be dealing with.

Stop eating 3+ hours before bed.

Twilight App on android or bluelight filter setting on iphone.

Blue light filter on TV or don't watch it at all. Get redlights for your house or limit artificial light a lot.

That's a good start

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Thank you. I do some of the above, however will look to introduce some more.

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