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Thomas Goyette's avatar

I love the ppl training split you have. Really trying to bring up my delts (side and rear). Are these muscles you can train everyday because they are smaller muscles?

For example: could I train rear delts on push day and side delts on pull day and both on leg day?

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BowTied Biohacker's avatar

Hell yeah dude

That's exactly what I did when delts were lagging

Then they got too big 😂

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BowTiedShmedium's avatar

If one’s World of Warcraft character was on Test Cyp, how would they go about switching esters? i.e. Test Prop, Ace (E is obvious), if you’re feeling generous - dosing / timing for pwo TNE?

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BowTied Biohacker's avatar

If you want to go about it like a true turbo autist:

Calculate the equivalent weekly and daily doses of the new WoW ester to match your previous molecular testosterone intake.

Start with half the daily dose of the new ester 5-6 days after switching. Gradually increase the dose by approximately half the remaining difference every 5-6 days until you reach the full dose.

Example: 50% → 75% → 87.5% → 93.6% → 97% → full dose.

TNE timing: 30-60 minutes before raiding is perfect

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BowTiedShmedium's avatar

My blood elf aspires to be a turbo but is decidedly left curve, he will be plugging this into WoW’s native LLM to translate into his native speech

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BowTied Biohacker's avatar

Lets say you take 200mg test cyp per week

200mg of testosterone cypionate = 139.8mg of molecular testosterone and 60.2mg of cypionic acid

167mg of testosterone propionate is also equal to 139.8mg of molecular testosterone

167mg divided by 7 = 23.85mg but you can just do 25mg to make it easier

This means you wait 5-6 days for the cyp ester to clear by 50% because that's what the half life is, and start with 12.5mg of test p daily until another 5-6 days pass then you bump up to 18.75mg per day

make sense?

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BowTied Biohacker's avatar

Or you can just do it the left curve way (a favorite of ours) and just switch esters without even worrying about it haha. Might get a pimple or 2 on the first week but whatever!

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BowTiedShmedium's avatar

My blood elf would never. My orc on the other hand….

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Athan's avatar

Great to see you back, hope you've been well!

Got some brutal wake-up call labs + DEXA back.

Testosterone, Total: 564 ng/dL

Testosterone, Free: 92.9 pg/mL

SHBG: 30 nmol/L

Estradiol (E2): 41 pg/mL

Dihydrotestosterone (DHT): 26 ng/dL

Androstenedione: 98 ng/dL

Follicle-Stimulating Hormone (FSH): 2.7 mIU/mL

Luteinizing Hormone (LH): 3.0 mIU/mL

Prolactin: 5.0 ng/mL

PSA (Total): 0.9 ng/mL

PSA (Free): 0.3 ng/mL

PSA % Free: 33%

Cortisol (12:30 PM): 19.5 mcg/dL

DHEA Sulfate: 302 mcg/dL

Insulin-like Growth Factor 1 (IGF-1): 141 ng/mL

DEXA:

Total Weight: 185.2 lbs (84 kg)

Fat Mass: 49.6 lbs (22.5 kg)

Lean Mass: 129.6 lbs (58.8 kg)

Bone Mass: 6.1 lbs (2.8 kg)

Body Fat Percentage: 26.8% (69th percentile)

Visceral Fat Mass (VAT): 2.2 lbs (1.0 kg) (84th percentile)

Bone Density (BMD): 1.211 g/cm² (13th percentile)

Lean Mass Index (LMI): 19.7 kg/m² (64th percentile)

Appendicular Lean Mass Index (ALMI): 9.67 kg/m² (64th percentile)

Basically fat degen confirmed via labs. Irregular exercise, wild sleep schedule, binge drinking on weekends, inconsistent sun exposure -- I know I've gotta clean up the lifestyle.

Question: If you were me, what would your top priorities be? Thank you in advance and sorry for the data dump. There's a lot more but want to be respectful of your time and this forum.

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BowTied Biohacker's avatar

Top priorities would be getting out at sunrise, lifting 3-4x per week, eating 1g of protein per lb of bodyweight, losing 2 lbs of fat per week and going 3 months without drinking (anyone who can't do that has a substance abuse problem, which btw not judging - have had plenty struggles with that)

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Athan's avatar

Forgot to say 32 years old 5'9"

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Gator's avatar

On Limitless's website they have injectable BPC-157 in both its base form and acetate form. What are your thoughts on base vs. acetate forms of peptides? Is the difference negligible or is one form superior to the other?

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BowTied Biohacker's avatar

Acetate distributes into soft tissues better (maybe) and has a longer half life

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Brolep's avatar

Hi UM, i have been using Coway/Cukcoo to filter the tap water and drink. It’s popular here in Asia. Is the filtration process provided by these brand enough/safe?

If not, is there any water filter approved by UM?

Suggestion: I hope you could write a guide on proper water filtration 🙏🏼.

Thank you UM.

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BowTied Biohacker's avatar

I had to look it up but Coway reverse osmosis filter is nice! You'll want to add minerals though

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X Y's avatar

Is there a guide about applying a smaller amount of BPC-157 topically to the scalp after micro needling? It makes more sence to me than ingesting. Since ingesting will have body-wide effects. I only want the effects on the scalp.

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BowTied Biohacker's avatar

If that was possible, you'd have heard about it (especially on this substack)

BPC-157 is 1419.54 daltons

Stuff over ~500 daltons does not absorb through your skin

Not sure why you wouldn't want to heal your entire body though, as the inflammation in the rest of your body is highly tied to the inflammation in your scalp

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X Y's avatar

Perhaps small injections at the site then? The body is going to do the healing anyway. Peptide just pushes it. Healing whole body is more resource consuming (and moe risky, since this is a in-research compound) than healing just one part.

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Justin M's avatar

my total testosterone levels are currently medium to low (488) at 29 years old, but my free T is in healthy range (107) and DHT is medium to high range (39) (& estradiol is low end of range(25)). Practically speaking, would raising total T make me feel a tangible difference if my useable free T and DHT are already in a good place?

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BowTied Biohacker's avatar

Ah, you're mistaken but don't blame you. The modern DHT reference range has been altered. You know what it was in 1982? 68-195, with average DHT being 100ng/dl

This is much closer to how men are supposed to be/feel, so for your purposes I would consider yourself Low DHT

The ratio of testosterone to DHT is >10, which again, indicates androgen:estrogen imbalance skewed towards the estrogenic side of things

BTW 25 is now low end of the range for estradiol, and when your total T and DHT are that low, you are functionally high e2

So yes, losing bodyfat until you can see 6 pack abs and increasing total T, free T (107 is not high btw), and DHT will have a profound impact on your mental/physical health and performance

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RB7's avatar
Feb 25Edited

BTBH, due to your posts (here and twitter), I got an EMR-Tek Inferno and it's really improved my life, so thank you! Tried every supplement in the book for gut health and after a while it would go to shit again. Since inferno, gut health has been stellar, not to mention all the other benefits. Been also trying to block as much blue light as I can and focusing on circadian health.

As I work on circadian health, I've been learning about the importance of UVA/UVB but the problem is we get very little sun where I live. As I decide between Sperti Fiji or Vitamin D lamp, I wanted to know if it would be possible to accomplish a melanin renovation using one of these paired with Inferno? From POMC perspective the Sperti Vitamin D lamp seems be better as indicated in your light post.

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BowTied Biohacker's avatar

Nope! There's no alternative to the sunlight bro!

If I were you I'd focus on sun and then maybe save up the smaller krypton so you can get both UVA/UVB with RED/IR all coming from the same direction

Still, you won't be able to do too a full melanin renovation, but it could be useful for preparing you to spend a ton of time outside this summer and is also useful in the winter for maintaining the solar calus, POMC expression, etc

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RB7's avatar

Thank you so much for your feedback. Going to have to wait for the Krypton a bit (helping some family out and saving for ECOM). In the interim, if I wanted to improve POMC expression, would the Sperti UVB also help with that?

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Thomas's avatar

Best thing for acne scars/pitting? Would something like ghk-cu work best or something more like tretinoin and mandelic acid?

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BowTied Biohacker's avatar

Best stack would be something like topical mirror skin, oral BPC, blue light reduction, microneedling, tons of sunlight, circadian lifestyle, and a diet high in collagen w/ vitamin c supplement in every meal to max collagen synthesis pathways and improve redox

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Rob J's avatar

I am currently on low-dose retatrutide (3mg/week, divided into 2 doses). What is the longest that one should run something like this for? Any issue taking it long term (I.e, a year)?

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BowTied Biohacker's avatar

That's not a low dose brother! 1-2mg would be

The longer you take reta, the worse the ravenous rebound hunger is gonna be

Personally wouldn't run it longer for 3 months before tapering it to mitigate the later, probably using tirzepatide to taper actually, so glucagon receptors can get a rest

It's a very powerful fat loss compound and should be respected. If you aren't losing 2 lbs of fat per week on reta, on average, you should clean up the diet to get the most of your limited time on it

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BowTiedShmedium's avatar

Thots on cagrilinitide to taper off? Diff pathway to take pressure of GLP/GIP

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Jay Kurtz's avatar

Bloodwork posted below, but wondering if I need to be doing anything in particular in order to:

- Raise stress tolerance

- Increase energy

- Increase self-sustained drive

Ref. the last point I noticed this was sky-high when doing sub Q NAD+ and IM cerebrolysin but then dramatically dropped off when I stopped both. Restarted sub Q NAD but hasn't been remotely the same.

Now working on reducing T/DHT ratio based on previous bloods.

Started taking tribugen, cistamax, redaxin, tongkat 10% today.

Doing AM/PM sunlight, red light on at least 60 mins per day, resistance 2-3x per week, HIIT 3x per week, sauna 4x week, sleeping roughly 8 hours/night

Diet: yoghurt, honey, berries for breakfast, salmon/potatoes for lunch, generally pork/chicken and rice for dinner > 1 - 1.3g / lb protein

Currently sitting around 16/17% BF

*********

Bloods as of 3 days ago:

Trig: 0.66 mmol/L

HDL: 0.9 mmol/L

LDL: 2.9 mmol/L

Vit D: 55 ng/dl

Testosterone, Total: 773 ng/dL

Testosterone, Free: 13 ng/dL (1.7% total, have heard this can be up to 5%)

SHBG: 52 nmol/L

Estradiol (E2): 29 pg/mL

Dihydrotestosterone (DHT): 52 ng/dL (15:1 ratio, want to get this down to 5-8:1)

Follicle-Stimulating Hormone (FSH): 5.2 mIU/mL

Luteinizing Hormone (LH): 4.2 mIU/mL

Prolactin: 6.88 ng/mL

PSA (Total): 0.87 ng/mL

PSA (Free): N/A

PSA % Free: N/A

Cortisol (09 AM): 329 nmol/L

DHEA Sulfate: 12 umol/L

Fasting glucose: 4.7 mmol/L

Tests not done:

- IGF-1

******************

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Justin Nichols's avatar

What effect does bulking have on my testosterone levels? I want to build more muscle but also increase T and DHT. As long as the bulk doesn’t get out of control (past ~15%), is that the sweet spot for both goals?

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Chris's avatar

In your experience, what is the average difference in someone's estrogen when switching from daily cyp/enan to daily prop?

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BowTied Biohacker's avatar

Enough of a difference to matter. Not really sure how to quantify

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Rolo's avatar

Oral Ghk - CU better or equal to injectable?

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BowTied Biohacker's avatar

Hahaha orals not even close to injectable bro. Don't believe everything you see.

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Jasen W. Pratt's avatar

Favorite intraworkout? Either branded product or single ingredient additions

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BowTied Biohacker's avatar

They all suck. About to fix that.

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KK07's avatar

For DHT supplementing which supp (or combination of supps) has the best potential without being stimulating ? I have low tolerance to anything stimulating .

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