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Thomas Goyette's avatar

I love the ppl training split you have. Really trying to bring up my delts (side and rear). Are these muscles you can train everyday because they are smaller muscles?

For example: could I train rear delts on push day and side delts on pull day and both on leg day?

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BowTied Biohacker's avatar

Hell yeah dude

That's exactly what I did when delts were lagging

Then they got too big 😂

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BowTiedShmedium's avatar

If one’s World of Warcraft character was on Test Cyp, how would they go about switching esters? i.e. Test Prop, Ace (E is obvious), if you’re feeling generous - dosing / timing for pwo TNE?

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BowTied Biohacker's avatar

If you want to go about it like a true turbo autist:

Calculate the equivalent weekly and daily doses of the new WoW ester to match your previous molecular testosterone intake.

Start with half the daily dose of the new ester 5-6 days after switching. Gradually increase the dose by approximately half the remaining difference every 5-6 days until you reach the full dose.

Example: 50% → 75% → 87.5% → 93.6% → 97% → full dose.

TNE timing: 30-60 minutes before raiding is perfect

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BowTiedShmedium's avatar

My blood elf aspires to be a turbo but is decidedly left curve, he will be plugging this into WoW’s native LLM to translate into his native speech

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BowTied Biohacker's avatar

Lets say you take 200mg test cyp per week

200mg of testosterone cypionate = 139.8mg of molecular testosterone and 60.2mg of cypionic acid

167mg of testosterone propionate is also equal to 139.8mg of molecular testosterone

167mg divided by 7 = 23.85mg but you can just do 25mg to make it easier

This means you wait 5-6 days for the cyp ester to clear by 50% because that's what the half life is, and start with 12.5mg of test p daily until another 5-6 days pass then you bump up to 18.75mg per day

make sense?

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BowTied Biohacker's avatar

Or you can just do it the left curve way (a favorite of ours) and just switch esters without even worrying about it haha. Might get a pimple or 2 on the first week but whatever!

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BowTiedShmedium's avatar

My blood elf would never. My orc on the other hand….

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Brolep's avatar

Hi UM, i have been using Coway/Cukcoo to filter the tap water and drink. It’s popular here in Asia. Is the filtration process provided by these brand enough/safe?

If not, is there any water filter approved by UM?

Suggestion: I hope you could write a guide on proper water filtration 🙏🏼.

Thank you UM.

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BowTied Biohacker's avatar

I had to look it up but Coway reverse osmosis filter is nice! You'll want to add minerals though

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X Y's avatar

Is there a guide about applying a smaller amount of BPC-157 topically to the scalp after micro needling? It makes more sence to me than ingesting. Since ingesting will have body-wide effects. I only want the effects on the scalp.

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BowTied Biohacker's avatar

If that was possible, you'd have heard about it (especially on this substack)

BPC-157 is 1419.54 daltons

Stuff over ~500 daltons does not absorb through your skin

Not sure why you wouldn't want to heal your entire body though, as the inflammation in the rest of your body is highly tied to the inflammation in your scalp

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X Y's avatar

Perhaps small injections at the site then? The body is going to do the healing anyway. Peptide just pushes it. Healing whole body is more resource consuming (and moe risky, since this is a in-research compound) than healing just one part.

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Thomas's avatar

Best thing for acne scars/pitting? Would something like ghk-cu work best or something more like tretinoin and mandelic acid?

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BowTied Biohacker's avatar

Best stack would be something like topical mirror skin, oral BPC, blue light reduction, microneedling, tons of sunlight, circadian lifestyle, and a diet high in collagen w/ vitamin c supplement in every meal to max collagen synthesis pathways and improve redox

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Athan's avatar

Great to see you back, hope you've been well!

Got some brutal wake-up call labs + DEXA back.

Testosterone, Total: 564 ng/dL

Testosterone, Free: 92.9 pg/mL

SHBG: 30 nmol/L

Estradiol (E2): 41 pg/mL

Dihydrotestosterone (DHT): 26 ng/dL

Androstenedione: 98 ng/dL

Follicle-Stimulating Hormone (FSH): 2.7 mIU/mL

Luteinizing Hormone (LH): 3.0 mIU/mL

Prolactin: 5.0 ng/mL

PSA (Total): 0.9 ng/mL

PSA (Free): 0.3 ng/mL

PSA % Free: 33%

Cortisol (12:30 PM): 19.5 mcg/dL

DHEA Sulfate: 302 mcg/dL

Insulin-like Growth Factor 1 (IGF-1): 141 ng/mL

DEXA:

Total Weight: 185.2 lbs (84 kg)

Fat Mass: 49.6 lbs (22.5 kg)

Lean Mass: 129.6 lbs (58.8 kg)

Bone Mass: 6.1 lbs (2.8 kg)

Body Fat Percentage: 26.8% (69th percentile)

Visceral Fat Mass (VAT): 2.2 lbs (1.0 kg) (84th percentile)

Bone Density (BMD): 1.211 g/cm² (13th percentile)

Lean Mass Index (LMI): 19.7 kg/m² (64th percentile)

Appendicular Lean Mass Index (ALMI): 9.67 kg/m² (64th percentile)

Basically fat degen confirmed via labs. Irregular exercise, wild sleep schedule, binge drinking on weekends, inconsistent sun exposure -- I know I've gotta clean up the lifestyle.

Question: If you were me, what would your top priorities be? Thank you in advance and sorry for the data dump. There's a lot more but want to be respectful of your time and this forum.

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BowTied Biohacker's avatar

Top priorities would be getting out at sunrise, lifting 3-4x per week, eating 1g of protein per lb of bodyweight, losing 2 lbs of fat per week and going 3 months without drinking (anyone who can't do that has a substance abuse problem, which btw not judging - have had plenty struggles with that)

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Athan's avatar

Forgot to say 32 years old 5'9"

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Gator's avatar

On Limitless's website they have injectable BPC-157 in both its base form and acetate form. What are your thoughts on base vs. acetate forms of peptides? Is the difference negligible or is one form superior to the other?

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BowTied Biohacker's avatar

Acetate distributes into soft tissues better (maybe) and has a longer half life

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Rob J's avatar

I am currently on low-dose retatrutide (3mg/week, divided into 2 doses). What is the longest that one should run something like this for? Any issue taking it long term (I.e, a year)?

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BowTied Biohacker's avatar

That's not a low dose brother! 1-2mg would be

The longer you take reta, the worse the ravenous rebound hunger is gonna be

Personally wouldn't run it longer for 3 months before tapering it to mitigate the later, probably using tirzepatide to taper actually, so glucagon receptors can get a rest

It's a very powerful fat loss compound and should be respected. If you aren't losing 2 lbs of fat per week on reta, on average, you should clean up the diet to get the most of your limited time on it

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BowTiedShmedium's avatar

Thots on cagrilinitide to taper off? Diff pathway to take pressure of GLP/GIP

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Jay Kurtz's avatar

Bloodwork posted below, but wondering if I need to be doing anything in particular in order to:

- Raise stress tolerance

- Increase energy

- Increase self-sustained drive

Ref. the last point I noticed this was sky-high when doing sub Q NAD+ and IM cerebrolysin but then dramatically dropped off when I stopped both. Restarted sub Q NAD but hasn't been remotely the same.

Now working on reducing T/DHT ratio based on previous bloods.

Started taking tribugen, cistamax, redaxin, tongkat 10% today.

Doing AM/PM sunlight, red light on at least 60 mins per day, resistance 2-3x per week, HIIT 3x per week, sauna 4x week, sleeping roughly 8 hours/night

Diet: yoghurt, honey, berries for breakfast, salmon/potatoes for lunch, generally pork/chicken and rice for dinner > 1 - 1.3g / lb protein

Currently sitting around 16/17% BF

*********

Bloods as of 3 days ago:

Trig: 0.66 mmol/L

HDL: 0.9 mmol/L

LDL: 2.9 mmol/L

Vit D: 55 ng/dl

Testosterone, Total: 773 ng/dL

Testosterone, Free: 13 ng/dL (1.7% total, have heard this can be up to 5%)

SHBG: 52 nmol/L

Estradiol (E2): 29 pg/mL

Dihydrotestosterone (DHT): 52 ng/dL (15:1 ratio, want to get this down to 5-8:1)

Follicle-Stimulating Hormone (FSH): 5.2 mIU/mL

Luteinizing Hormone (LH): 4.2 mIU/mL

Prolactin: 6.88 ng/mL

PSA (Total): 0.87 ng/mL

PSA (Free): N/A

PSA % Free: N/A

Cortisol (09 AM): 329 nmol/L

DHEA Sulfate: 12 umol/L

Fasting glucose: 4.7 mmol/L

Tests not done:

- IGF-1

******************

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Justin Nichols's avatar

What effect does bulking have on my testosterone levels? I want to build more muscle but also increase T and DHT. As long as the bulk doesn’t get out of control (past ~15%), is that the sweet spot for both goals?

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Chris's avatar

In your experience, what is the average difference in someone's estrogen when switching from daily cyp/enan to daily prop?

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BowTied Biohacker's avatar

Enough of a difference to matter. Not really sure how to quantify

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Rolo's avatar

Oral Ghk - CU better or equal to injectable?

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BowTied Biohacker's avatar

Hahaha orals not even close to injectable bro. Don't believe everything you see.

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Jasen W. Pratt's avatar

Favorite intraworkout? Either branded product or single ingredient additions

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BowTied Biohacker's avatar

They all suck. About to fix that.

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KK07's avatar

For DHT supplementing which supp (or combination of supps) has the best potential without being stimulating ? I have low tolerance to anything stimulating .

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Brendan's avatar

Can someone explain zone 2 cardio without sending me to a paywall

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BowTied Biohacker's avatar

It's cardio at 60-70% of your max hr

Light cardio

Burns maybeee 5-600 cals an hour tops

Good for fat loss and health

Btw that was the easiest question you could have popped into any search engine or AI and gotten a good answer, not sure what you mean by getting sent to a paywall 😜

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JC's avatar

Been on TRT for a couple years now. 100 mg/week has had me sitting at 900-1,000 Test levels. Decided to work up my dose slowly towards a mild blast level to help push my physique and overall drive. I push my dose a bit, feel amazing for about a week, then it fades. Push it, feel great, it fades. Sitting at 200 mg/week now, and wondering why I’m not continuously feeling great at these levels. Thanks

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BowTied Biohacker's avatar

You'd have to go into more details about what feeling great means to you, and what is happening when you're not feeling great

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JC's avatar

Most of the time I just feel blah. Classic low T symptoms, which is frustrating considering my T, free T, DHT etc levels. When I bump my dose I feel like I want to. Energized, alive, driven, never tired, tons of stamina. But then I fades after about a week.

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BowTied Biohacker's avatar

High e2

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JC's avatar

Awesome thanks. Recent bloodwork just came back, E2 at 70, highest level I’ve had. Also been feeling overly emotional lately, which is odd for me. I think you’re right, will adjust this a bit and see how I feel. Appreciate the insight.

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BowTied Biohacker's avatar

Loll.....should be half that

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