61 Comments
Apr 9Liked by BowTied Biohacker

33M on TRT (120mg/weeks) My FSH and LH both came super Low on a recent blood test to the point it didn't even give a value. My last HCG pin 5000IU was 4 days prior. Because of the low levels, I'm concerned about the long term implications of this fertility wise.

Should I get bloods done closer to the HCG pin, come off completely for a while or try something else? Thank you!

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author

Lol. DId you not know that TRT suppresses LH & FSH??

Why are you on TRT in the first place? Did you genuinely need it? If so, you may have had fertility issues to begin with.

HOWEVER, hCG is pro-fertility. It is not going to *increase* LH on a blood test, it simply acts like LH at the LH receptors. So there's a very good chance you have a bunch of sperm. Want to actually know? Get a semen analysis.

As far as FSH goes, it's a driver of spermatogenesis. hCG does not act like FSH. If hCG alone isn't sufficient enough for fertility puproses there is HMG (a combo of LH & FSH) or rFSH. There is also the option of getting off TRT and running hCG+ HMG/rFSH monotherapy or enclomiphene monotherapy under doctor supervision when it's time to have kids. It's not a big deal brother

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Ha I know it suppresses both but didn't know it would suppress it this much LOL.

That said, good to know there are other options as well.

Thanks again BTB!

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Apr 8Liked by BowTied Biohacker

Hello, I’m a college baseball player having taken a variety of supplements. Currently reassessing my regimen and would like to get your take on things I should add/subtract.

I’m currently taking-

Morning:

.5 oz beef liver, 4 oz heart, 5-MTHF 400mg (E.O.D.), Lutein/zeaxanthin, 6mg boron citrate, Biogaia l reuteri, 10g Creatine monohydrate w peak atp

Bed:

400 mag Bisglycinate, 3g glycine, Vignatex (for mung bean extract), 2g ascorbic acid, 15-30mg CBD isolate (sometimes)

Pregame:

Rotation between-

1. Nicotine lozenge 2mg/ Alpha gpc 300mg*

2. Phenylpiracetam 150mg/agpc 300mg*

*sometimes also caffeine and/or teacrine

3. Adderall 5-10mg

Practice (not all together):

Noopept 10mg, agpc 300mg, sabroxy, caffeine, bromantane, nicotine

On the radar but not currently taking:

Cistamax/cistanche, tributen/tribulus, tongkat, mag acetyl taurate

Any suggestions would be greatly appreciated. Even just a 1% improvement in energy, focus, or spacial awareness/depth perception w/o compromising health would be great. New subscriber so if this is too detailed of a question I apologize. Thanks!

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author

You're doing a half ounce of beef liver daily? That's a lot bro, maybe every 2-3 days lol.

I'd make sure to egg max or supplement with CDP Choline and only take a noopept, agcp or racetam 2-3x per week max to avoid acetylcholine depletion and receptor downregulation.

I'd swap Vignatex for Tribuben, you'll like it. Maybe add some canna to the dopaminergic stack as well. Catuaba and Fo Ti are also incredibly underrated.

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Apr 8Liked by BowTied Biohacker

Just for fun sake, if you had one year left to live,what would your stack be?

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author

I'd probably do a bunch of recreational drugs not gonna lie.

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Coming off a 16 week cut in the next 2-3 weeks. Dropped 22lbs so far, thanks to your protocol - thanks!

Are there any hormonal / muscle loss downsides to finishing off my cut with a 72 hour fast?

Thanks!

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author

I don't think so bro, I'd go for it

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Sup mate. I quit alcohol completely before 2 yrs after 10 yrs drinking everyday. Not big amounts but regularly. Is there something which I can try that have effects compared like dopamine and gaba boost from alcohol? I know for kava but it's expensive and hard to get in Europe. Heard also for b12+taurine occasionally. I am 31y old, doing a lot of sun exposure and eating healthy. Still my dopamine baseline levels are quite low. I work full time poker and crypto so this is contributing for my low dopamine baseline too I guess.

P. S.: it should not be stimulating at all cuz triggers anxiety very easily.

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When it comes to injecting test, you previously stated, "The more frequent injections, the lower your DHT & estradiol will be (side effects) and the closer you are to a natural diurnal pulse, which is a lot healthier for sleep & overall health"

With the understanding that we want to maximize DHT, are the benefits of more frequent injections worth the trade-off of lower DHT conversion?

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author

Propiionate ester daily seems to maxx dht and minimize aromatization to e2

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Ideally don't want to pin more frequently than EOD. Following this schedule, would propionate be more suitable than enanthate or cypionate for maximizing DHT and minimizing E2? Do the esters make a difference at that frequency if dosed correctly?

Thanks for your insight.

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author

Yes they would be & yes they do. Big difference? Not necessarily, but noticeable in feel & physique ime

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hi, skinnyfat here, will 500-1000 calorie deficit (keto or nonketo) will make it difficult achieving boners and / or sustaining boners? (my main goal is optimizing hormones for optimal sexual intercourse, I have high money, low time, and accepting any diet)

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author

Being skinnyfat is the worst thing for your hormones and erectile quality

Sure a caloric deficit can reduce libido, especially if you aren't hitting your micronutrient, but being skinny fat is worse. Get lean ASAP. 6 PACK ABS ASAP. 10% bodyfat.

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I'll do that!!!! Thank you!!!!!

in the process to get 6 pack abs 10%bf, which topic should I prioritize to keep/improve erectile quality while cutting bodyfat? heavylifting/running at X heart rate/kegels/supplements/fadogiaagrestis/tongkatali/etc

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Going to try bpc-157 and sodium butyrate for ulcerative colitis which has been flaring past couple days, have these on hand for this reason. Do you have any other recommendation? What would you say for dosing of the items I mentioned

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Telmisartan question:

I have hypertension forever and recently got back on TRT (25mg EOD) and saw in your posts that you recommend Tadalafil and Telmisartan.

https://x.com/bowtiedum/status/1611769135679012865?s=46

I have read about Potassium and Telmisartan - but at 20mg or 40mg should I be concerned about it or it’s no biggie at such doses?

On my last bloodwork a few weeks ago potassium levels were 4.21 mEq/l.

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author

Probably not a concern at 20 or 40mg but always confirm with bloodwork and doctor

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Can someone be high in freeT and low in DHT? If so whats the best way to increase DHT, naturally.

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Boring question but what does your grocery list normally look like?

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Is there any downsides of long term daily Tadalafil usage? Like body gets used to blood pressure being lowered so tries to adjust etc. Might be stupid question was just wondering how that might work

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What protocol would you recommend for a receding hair line?

Have very thick hair, but want to sort the hairline now, before it becomes worse

Thanks!

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author

Very thick hair, but receding? Doesn't make sense unless you're talking about losing some hair in the temple region which is a normal part of aging? Google "Norwood Chart"

If you're I or II, literally just age bro don't worry about it.

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Hi brother, Is it possible to burn fat on daily maintenance via fasting 16h (burning fat) and building new muscle tissue in those 8h window?

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author

Naturally? Probably not unless you have low muscle mass or are obese

With performance enhancing drugs? Absolutely

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If you had a 6 year old child who'd just finished a course of antibiotics for an infection, what would you do to help restore their gut microbiome? diet, supplements and anything else you can think of that might help.

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author

I'd give them psyllium (prebiotic), probiotic foods like kefir, sour kraut, greek yogurt, kimchi, etc, and a post biotic like sodium butyrate. Perhaps a little glutamine thrown in the kefir shake with some blended fruit.

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Best way to go from 13-9%, (how often to fast and ho much muscle loss should I expect maybe how to minimize it) when free T is already 1,6% of Total only.

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