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BowTied Biohacker's avatar

I don't think it makes much sense to compare a necessary nutrient to a drug LOL but I'll try

Phenibut activates GABA b receptors, magnesium blocks calcium channels at NMDA receptors

Phenibut will get you high, magnesium won't

Your body needs magnesium daily, your body does not need phenibut

Magnesium makes you naturally calm, phenibut is a calming DRUG with druglike effects that forces your brain to chill out

Idk I feel weird writing all that, please don't make me compare nutrients to drugs again hahaha

Stay swell n swole

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AnonM's avatar

I asked about Phenibut vs Selank, not magnesium. There’s few studies and wanted your opinion as I’m not an expert in understanding these

Ex: https://pubmed.ncbi.nlm.nih.gov/34396551/

Thanks! :)

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BowTied Biohacker's avatar

LOL sorry, I got this comment right after I posted the magnesium guide.

You'd be surprised how many people ask that question.

So selank is a GABA a positive allosteric modulator, meaning it makes GABA A receptors more sensitive to your own GABA. Phenibut is a GABA b agonist, meaning it acts like GABA and directly binds to the GABA b receptors. GABA B activation has downstream dopaminergic effects and can have more a "stimulating".

Selank also increases endorphins by inhibiting the enzyme that degrades them, so that adds to selanks unique effect.

Overall selank feels more natural, clear headed and calm while phenibut is more of a euphoric "I'm on drugs" and sedative feeling. Any other questions I can answer? Happy to help!

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