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M.'s avatar

Hair Loss protocol:

Is there a difference between injection of GHK-Cu and topical use?

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BowTied Biohacker's avatar

They're the same for hair loss but the injectable will give you full body benefits too

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Fab's avatar

Any suggestions for allergies: causes/solutions/are antihistamines ok?

Some info: 26F has had terrible allergies her second year in Sydney. Started in March, never had allergies before in North America. They stopped when she went away for 2 months and started again when she got back to Sydney just now.

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alex's avatar

Myself + others have noted that it's often easier to work after sleep deprivation (doing an all-nighter then working into next day, working after 24+ hours awake type deal, etc)

Someone who tweeted about this (wish I could find it) says it's because they are ADHD - I don't believe I am ADHD, but I notice this phenomenon too

Wondering if you know what or why this could be OR how to replicate it supplementally (idk what to ask exactly as maybe it's just, being tired = less energy = eaier to sit and work? idk)

Thanks - and sorry if it's hard question to answer

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BowTied Biohacker's avatar

This is the magic of high cortisol

Except not really, because if you do this often you'll mess with your adrenal function and feel chronically fatigued and brain fogged :)

If you want to do it the right way (my preference) it's the boring and hard stuff: 1) clean diet with all vitamins and minerals accounted for 2) plenty of sunlight 3) plenty of aerobic and anaerobic exercise 4) optimized hormones

Otherwise you can take stimulants which are bad for your health, addictive, and also stop working

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James's avatar

Hi, do you know of anything supplement or dietary wise that can help with jaundice from Gilbert’s Syndrome?

Thanks!

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BowTied Biohacker's avatar

this is a question for your doctor, but if I had Gilbert's syndrome I'd focus on liver detox pathways, so: NAC, TUDCA, black seed oil, and inositol

Also make sure I'd have no vitamin or mineral deficiencies and try to eat a more low carb/keto diet

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James's avatar

Thanks man

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Dev Patel's avatar

What are the best ways to increase hunger? I am trying to put on some weight and am working on 4-5 times a week but it seems that i struggle to eat enough food.

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BowTied Biohacker's avatar

I mean the easy answer is MK-677, but that will cause some side effects haha

If you have trouble eating, I always found a shake made from kefir, protein powder, banana & oats is a good way to start first thing in the morning to spike insulin and get the digestive system going

Sushi rice instead of regular rice is another good hack because it digests very quickly, making you hungry again sooner, and is more calorie dense

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Jesse's avatar

You have any protocol for reducing post exercise cortisol spike? I get it pretty bad if I work out in the morning. Especially if doing any sort of HIIT

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BowTied Biohacker's avatar

Is this confirmed with labs?

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Edn's avatar

I am currently 18 and I noticed I look similar to the example of the average man in the 2010s showcased in your dht article(boyish appearance, 5' 6", 130lbs). My T is decent, as well as my free T and thyroid(681 ng/dl, free T in the higher range), I tend to be more lethargic during school but overall I feel pretty healthy.

My question is would lifestyle changes make me look and feel much more manly, or would you recommend exogenous alternatives?

Also, is @AlphaGels on twitter legit? What would you recommend aside a dht gel?

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User's avatar
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Aug 9
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Edn's avatar

Appreciate you and your work thanks🙏🏻

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JD's avatar

24/7 songs blasting in my head. Glutamate/gaba problem? Thanks

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BowTied Biohacker's avatar

Yeah, could be excess glutamate, too low GABA for sure

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Thomas's avatar

When do you typically do your scalp micro needling? I tried looking it up and every person seemed like they have their own set of rules as to when it's actually fine to do it rofl. Don't wanna end up with a scalp infection or something stupid. I imagine after a shower and hair has completely dried would be fine correct? (Disinfecting the roller every time of course.)

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BowTied Biohacker's avatar

yeah that's a good time to do it for sure. I did it whenever and never got infections, but I'm not usually dirty and have a good immune system so never really cared

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Nathaniel's avatar

Have you any suggestions or protocol for someone dealing with an autoimmune skin flare up? Specifically hives or something hives-like?

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BowTied Biohacker's avatar

I mean you can always address the root cause: pretty much every case of autoimmune disorder you have light & gut issues: people living in the wrong climates for their skin type, not spending time outside, artificial light exopsure in the evening/circadian dysregulation, and a diet consisting of foods that are inflammatory to that person

But as far as dealing with hives on the spot? The solutions like antihistamines and topical corticosteroids are just bandaids. gotta address the root cause by fixing light environment and elimination diet

BTW i hear some people have had success with these types of things on oral bpc and/or injectable Ta1, but no guarantees

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BowTied Gamblooor's avatar

Where does injectable L-Carnitine sit in terms of 5AR up-regulation?

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BowTied Biohacker's avatar

What do you mean?

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BowTied Gamblooor's avatar

Does it help in up-regulating 5AR?

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BowTied Biohacker's avatar

It upregulates AR so it'll give you the feeling of more DHT even though you won't have more DHT

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calm's avatar

Potentially hard one:

How could a person take a very powerful level stimulant like an amphetamine on an indefinite basis without getting burned out?

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BowTiedEggplant's avatar

What’s a good sleep protocol for a guy with Parkinson’s (stage 1)?

He’s tried magnesium acetyl taurate, glycine, taurine, l theanine

Im suspecting it’s a spasticity issue for him

His deep sleep score is pretty fucked (less than 20 min per night)

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BowTied Biohacker's avatar

I mean that's usually when the doctors prescribe something like a caber or prami and it helps

Grim's easy journey + mulungu + blue lotus would probably do the trick though

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BowTiedEggplant's avatar

Thanks brother 🤝

Bromantane worth it to help with his Parkinson’s?

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Bobo's avatar

How do i build that big “barrel” type body that a lot of combat athletes have? Like Gervonta Davis and Nicky Rod. Guessing it’s just neck, lats, and a ton of core work (on top of being generally muscular elsewhere)

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BowTied Biohacker's avatar

I'm not really seeing it. You don't have to lift weights to look like those guys, but it can help to do some heavy deadlifts as those hit the neck/lats/core a ton. Those physiques are mostly just the result of being lean and doing a bunch of fast twitch work like mma training.

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Wolf's avatar

IBS protocol?

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BowTied Biohacker's avatar

oh boy. this is an entire huge post hahaha and it still depends on the individual. most general protocol, I guess would be:

1) clear everything out with a bunch of mag citrate

2) fast for 3 days

3) STRICT carnivore diet for a while, absolutely NO dairy, alcohol, coffee, artificial sweeteners

4) oral BPC (obviously) & KPV 4x day

5) slowly introduce other foods back in to identify which ones cause inflammatory response and avoid those

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The Big J's avatar

Looking back on what you know about DHT. Will you ever get back on exo? Or cause of the uptick in 5AR are you going for natty production? I’ve been off exo DHT for about 2-3 weeks and even tho I feel it a bit, feels like I’m leaving something on the table.

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BowTied Biohacker's avatar

I will probably reintroduce a very small dose like 20mg molar DHT per week, but I've gotten some great 5AR upregulation and have a natty ~6.5:1 ratio

Keep in mind, I was already pretty high DHT before exo (8.5:1) because of all the fast twitch training I've done for years

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